Ulcer healing activity of Mumijo aqueous extract against acetic acid induced gastric ulcer in rats
نویسندگان
چکیده
منابع مشابه
Effect of Ziziphora clinopodioides L. Aqueous Extract on Peptic Ulcer Induced by Acetic Acid in Rats
Article Type Research Article Authors Mousavi Mobarake Sh.* MSc, Rahnama M.1 PhD, Bigdeli M.R.2 PhD, Nasiri Semnani Sh.3 PhD
متن کاملEffects of trimoprostil on healing and recurrence of acetic acid-induced gastric ulcer in rats.
Chronic gastric ulcers were produced by injection of 20% acetic acid (0.05 ml) into the submucosal layer of the rat stomach in order to determine the effects of the prostanoid trimoprostil on the healing and recurrence of ulcers. Local injection of acetic acid solution produced large demarcated ulcers in all animals on day 5, which rapidly decreased to reach low levels on days 40-80 and then be...
متن کاملEffects of novel anti-inflammatory compounds on healing of acetic acid-induced gastric ulcer in rats.
Nonsteroidal anti-inflammatory drugs often cause development of significant GI lesions. Selective inhibitors of prostaglandin G/H synthase/cyclooxygenase-2 (PGHS-2) enzyme and some dual inhibitors of PGHS/5-lipoxygenase (5-LO) enzymes have been reported to be potent anti-inflammatory compounds that carry a much lower risk of having GI irritating effects. We have evaluated the anti-inflammatory ...
متن کاملAccelerated Ulcer Healing and Resistance to Ulcer Recurrence with Gastroprotectants in Rat Model of Acetic Acid-induced Gastric Ulcer
Quality of ulcer healing (QOUH) is defined as ideal ulcer healing featuring with the fine granular ulcer scar, high functional restoration and the resistance to recurrence. This study was designed to compare the rates of QOUH achievement in rat gastric ulcer model between acid suppressant treated group and gastroprotectant treated group accompanied with elucidations of molecular mechanisms. Ser...
متن کاملRabbit gastric ulcer models: comparison and evaluation of acetic acid-induced ulcer and mucosectomy-induced ulcer
In this study, we examined rabbit gastric ulcer models that can serve as more clinically relevant models. Two types of ulcer model were studied: acetic acid-induced ulcers (AAU) and mucosal resection-induced ulcers (MRU). For AAU, rabbit gastric mucosa was exposed by median laparotomy and treated with bottled acetic acid. MRU was examined as a model for endoscopic mucosal resection (EMR). Norma...
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ژورنال
عنوان ژورنال: Journal of Pharmacy and Bioallied Sciences
سال: 2015
ISSN: 0975-7406
DOI: 10.4103/0975-7406.148739